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Volume 65, Issue 1, July 2023

Articles

Minimum Inhibitory Concentration (MIC) and LC-MS analysis of Phellinus pectinatus : A species of wild macrofungi (Mushroom) collected from North Western Himalayan, Uttarakhand, India

https://doi.org/10.20324/nelumbo/v65/2023/172415

Published 2023-07-01

  • Gaurav Kothiyal
    • ,
  • Keerti Singh

Gaurav Kothiyal
Department of Microbiology, Uttaranchal (P.G.) College of Bio-Medical Sciences & Hospital (UCBMSH ) Dehradun-248 001, Uttarakhand

Keerti Singh
Department of Microbiology, School of Paramedical & Allied Health Sciences, SGRR University Dehradun-248 001, Uttarakhand

Abstract

Antimicrobial resistance has emerged as a global public health problem in recent years. Because of the indiscriminate use of antibiotics, pathogenic microorganisms have developed resistance to many types of drugs. Due to this, many types of serious treatment problems have been encountered. In such a situation, there is a need to explore new compounds from new natural sources. Wild macrofungi (mushrooms) can be seen as a new natural resource. On which not much research work has been done so far. There is a lot of diversity in the nature of wild macrofungi. On which research work can be done to develop new medicinal products in the near future. The present study aims to investigate the Minimum inhibitory concentration (MIC) against selected organisms by methanol extract of Phellinus pectinatus and identify the non-volatile compounds present in the extract by LC-MS analysis. The present results suggest that P. pectinatus may indeed be a potential source of antimicrobial agents as well as bioactive compounds.

Keywords

Antimicrobial, Phellinus pectinatus, Minimum Inhibitory Concentration, LC-MS.

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