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Phytochemical Analysis and Anticancer Activity of Gracilaria tenuistipitata C.F.Chang & B.-M.xia against Breast Cancer MCF- 7 Cells


The marine algae Gracilaria tenuistipitata was collected from the backwater area of the Kakinada coast, Andhra Pradesh, India. The main objective of this study is to determine the preliminary phytochemicals and anti-cancer activity of red seaweed. The anticancer activity was examined in ethyl acetate extract using a 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay against the breast cancer cell line (MCF-7). Seven compounds were identified in the ethylacetate extract of G. tenuistipitata and the major components were Oleic Acid, Phytol, and Squalene, which were found to have antimicrobial, antioxidant, anti -inflammatory, antitumor, and cancer preventive properties. The results of this research indicated that the ethylacetate extract of G. tenuistipitata could be the source for anti-cancerous potential against breast cancer cells.


Red Seaweed, Phytochemical, GC-MS, Cytotoxicity.



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